Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12575508 | 0.94 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTKMT2AHDAC1 | |
| SCHEMBL15907908 | 0.89 | LMNA (0.43) | ALDH1A1LMNAMAPTKMT2AHDAC1 | |
| SCHEMBL15907906 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTKMT2AHDAC1 | |
| SCHEMBL15907910 | 0.84 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTKMT2AHDAC1 | |
| SCHEMBL30833293 | 0.81 | EHMT2 (0.48) | ALDH1A1LMNAMAPTKMT2AHDAC1 | |
| SCHEMBL14984823 | 0.81 | EHMT2 (0.48) | ALDH1A1LMNAMAPTKMT2AHDAC1 | |
| SCHEMBL15140934 | 0.80 | EHMT2 (0.47) | ALDH1A1LMNAMAPTKMT2AHDAC1 | |
| SCHEMBL18369713 | 0.80 | EHMT2 (0.47) | ALDH1A1LMNAMAPTKMT2AHDAC1 | |
| SCHEMBL31290207 | 0.80 | EHMT2 (0.47) | ALDH1A1LMNAMAPTKMT2AHDAC1 | |
| SCHEMBL29796129 | 0.80 | EHMT2 (0.47) | ALDH1A1LMNAMAPTKMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213641-A1 | POLYMERIC NANOPARTICLES FOR DRUG DELIVERY | INSTITUT QUIMIC DE SARRIA (ES) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213641-A1 | POLYMERIC NANOPARTICLES FOR DRUG DELIVERY | CD44, MKI67, CD63 | ALDH1A1 1535/4885LMNA 469/4885MAPT 2749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.