Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15907911 | 0.89 | ALDH1A1 (0.39) | LMNAALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL15907906 | 0.86 | ALDH1A1 (0.41) | LMNAALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL17253259 | 0.84 | LMNA (0.47) | LMNAALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL12575508 | 0.83 | ALDH1A1 (0.40) | LMNAALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL15907910 | 0.82 | ALDH1A1 (0.54) | LMNAALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL17748162 | 0.80 | ALDH1A1 (0.42) | LMNAALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL17752518 | 0.80 | ALDH1A1 (0.42) | LMNAALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL12575507 | 0.80 | LMNA (0.39) | LMNAALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL14817461 | 0.80 | HDAC1 (0.45) | LMNAALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10311158 | 0.77 | ALDH1A1 (0.47) | LMNAALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213641-A1 | POLYMERIC NANOPARTICLES FOR DRUG DELIVERY | INSTITUT QUIMIC DE SARRIA (ES) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213641-A1 | POLYMERIC NANOPARTICLES FOR DRUG DELIVERY | CD44, MKI67, CD63 | LMNA 469/4885ALDH1A1 1535/4885MAPT 2749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.