Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107148 | 0.89 | GAA (0.70) | GAALMNAL3MBTL1NPC1TDP1 | |
| SCHEMBL16270203 | 0.87 | GAA (0.50) | GAALMNAL3MBTL1NPC1TDP1 | |
| SCHEMBL15908118 | 0.86 | L3MBTL1 (0.49) | GAALMNAL3MBTL1NPC1TDP1 | |
| SCHEMBL16270225 | 0.84 | L3MBTL1 (0.48) | GAALMNAL3MBTL1NPC1TDP1 | |
| SCHEMBL12646476 | 0.84 | GAA (0.64) | GAALMNAL3MBTL1NPC1TDP1 | |
| SCHEMBL4217211 | 0.83 | GAA (0.49) | GAALMNAL3MBTL1NPC1TDP1 | |
| SCHEMBL4217209 | 0.83 | GAA (0.49) | GAALMNAL3MBTL1NPC1TDP1 | |
| SCHEMBL5111012 | 0.82 | LMNA (0.69) | GAALMNAL3MBTL1NPC1TDP1 | |
| SCHEMBL24871065 | 0.81 | HPGD (0.57) | GAALMNAL3MBTL1NPC1TDP1 | |
| SCHEMBL1550768 | 0.81 | GAA (0.60) | GAALMNAL3MBTL1NPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213688-A1 | Absorbable Multi-Putty Bone Cements and Hemostatic Compositions and Methods of Use | ABYRX, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-20140213688-A1 | Absorbable Multi-Putty Bone Cements and Hemostatic Compositions and Methods of Use | ABYRX, INC. (US) | 2014-07-31 | — | — | US | disclosed |