Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116437 | 0.92 | PTGS2 (0.66) | LMNAGAAL3MBTL1PTGS2MEN1 | |
| SCHEMBL17365269 | 0.86 | PTGS2 (0.60) | LMNAGAAL3MBTL1PTGS2MEN1 | |
| SCHEMBL12061812 | 0.86 | GAA (0.66) | LMNAGAAL3MBTL1NPC1HPGD | |
| SCHEMBL197602 | 0.84 | PTGS2 (0.58) | LMNAGAAL3MBTL1PTGS2MEN1 | |
| SCHEMBL7693991 | 0.84 | PTGS2 (0.58) | LMNAGAAL3MBTL1PTGS2MEN1 | |
| SCHEMBL13935133 | 0.84 | PTGS2 (0.58) | LMNAGAAL3MBTL1PTGS2MEN1 | |
| SCHEMBL4264046 | 0.84 | PTGS2 (0.58) | LMNAGAAL3MBTL1PTGS2MEN1 | |
| SCHEMBL10364396 | 0.84 | PTGS2 (0.58) | LMNAGAAL3MBTL1PTGS2MEN1 | |
| SCHEMBL10174361 | 0.84 | GAA (0.55) | LMNAGAAL3MBTL1NPC1TDP1 | |
| SCHEMBL1107148 | 0.82 | GAA (0.70) | LMNAGAAL3MBTL1NPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132496-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF, AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-06-05 | — | — | US | claimed |
| EP-4626864-A1 | LINEAR HETEROARYL DIAMIDE IRE1/XBP1S ACTIVATORS | Protego Biopharma, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118801-A1 | LINEAR HETEROARYL DIAMIDE IRE1/XBP1S ACTIVATORS | PROTEGO BIOPHARMA, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| CN-117645540-A | Preparation method of chlorophenoxycarboxylate | 山东润博生物科技有限公司 | 2024-03-05 | — | — | CN | disclosed |
| US-20240009169-A9 | PPARG Modulators for the Treatment of Osteoporosis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-01-11 | — | — | US | disclosed |
| EP-3181545-B1 | PROCESS FOR THE PREPARATION OF OSPEMIFENE | SHIONOGI & CO (JP) | 2023-11-01 | — | — | EP | disclosed |
| US-20230072933-A1 | PPARG Modulators for the Treatment of Osteoporosis | SCRIPPS RESEARCH INST (US) | 2023-03-09 | — | — | US | disclosed |
| US-20230072933-A1 | PPARG Modulators for the Treatment of Osteoporosis | SCRIPPS RESEARCH INST (US) | 2023-03-09 | — | — | US | disclosed |
| CN-114075099-A | Synthetic method of p-methyl anisole or stable isotope marker thereof | 上海安谱实验科技股份有限公司 | 2022-02-22 | — | — | CN | disclosed |
| US-10744117-B2 | PPARG modulators for the treatment of osteoporosis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-08-18 | — | — | US | disclosed |
| WO-2007000550-A2 | NOVEL INDOLINE COMPOUNDS | LABORATOIRES FOURNIER S.A. (FR) | 2007-01-04 | — | — | WO | disclosed |
| WO-2005087761-A1 | NOVEL CYCLOALKYL-CONTAINING 5-ACYLINDOLINONES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PRODUCTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-09-22 | — | — | WO | disclosed |
| CN-1008737-B | Process for preparing benzo [1] oxy [5] thiacycloheptene derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-07-11 | — | — | CN | disclosed |
| CN-85104426-A | Benzo [ 1 ] oxy [ 5 ] thiacycloheptene derivatives, their production and use | — | 1986-04-10 | — | — | CN | disclosed |
| US-4304907-A | Bicyclo lactone intermediates for prostaglandin analogs | THE UPJOHN COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
| US-4303796-A | 16-Phenoxy prostaglandin F2α analogs | THE UPJOHN COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
| US-4116988-A | 16-Phenoxy prostaglandin E1 analogs | THE UPJOHN COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-4116989-A | 16-Phenoxy prostaglandin F1α analogs | THE UPJOHN COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-4087616-A | 16-Phenoxy prostaglandin A2 analogs | THE UPJOHN COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-3931279-A | 5-Oxa prostaglandin F2.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132496-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF, AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | F12, F11, F2 | LMNA 2898/4885GAA 370/4885L3MBTL1 4590/4885 |
| US-20230072933-A1 | PPARG Modulators for the Treatment of Osteoporosis | PPARG, PPARA, PPARD | LMNA 2029/4885GAA 3259/4885L3MBTL1 2810/4885 |
| US-10744117-B2 | PPARG modulators for the treatment of osteoporosis | PPARG, PPARA, PPARD | LMNA 2029/4885GAA 3259/4885L3MBTL1 2810/4885 |
| US-20240009169-A9 | PPARG Modulators for the Treatment of Osteoporosis | PPARG, PPARA, PPARD | LMNA 2029/4885GAA 3259/4885L3MBTL1 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.