SCHEMBL15908373

SCHEMBL15908373

CC(=O)CNCP(C)(C)=O

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.32
ALDH1A1 P00352 2/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13850048 0.80 ENO1 (0.32) ALDH1A1TDP1
SCHEMBL690784 0.74
SCHEMBL15908372 0.74 CA2 (0.31)
SCHEMBL27722358 0.72 ALDH1A1 (0.41) HTTALDH1A1TDP1
SCHEMBL20437638 0.69
Acetic Acid SCHEMBL27521436 0.69 FFAR3 (0.47) HTTALDH1A1TDP1
Oxalic Acid SCHEMBL1401228 0.67 ALDH1A1 (0.37) HTTALDH1A1TDP1
SCHEMBL26950116 0.67 PAOX (0.38) HTTALDH1A1TDP1
SCHEMBL1908517 0.67
Water SCHEMBL9592390 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9388202-B2 Luminescent probes for biological labeling and imaging, method for preparing same CENTRE NATIONAL DE LA RECHRCHE SCIENTIFIQUE (FR) 2016-07-12 US disclosed
US-9328088-B2 Luminescent probes for biological labeling and imaging, and process for preparing the same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-05-03 US disclosed
US-20140228553-A1 LUMINESCENT PROBES FOR BIOLOGICAL LABELING AND IMAGING, METHOD FOR PREPARING SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2014-08-14 US disclosed
US-20140213777-A1 LUMINESCENT PROBES FOR BIOLOGICAL LABELING AND IMAGING, AND PROCESS FOR PREPARING THE SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2014-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140213777-A1 LUMINESCENT PROBES FOR BIOLOGICAL LABELING AND IMAGING, AND PROCESS FOR PREPARING THE SAME SLC30A6, SLC30A7, SLC39A7 HTT 2668/4885ALDH1A1 2243/4885TDP1 2735/4885
US-20140228553-A1 LUMINESCENT PROBES FOR BIOLOGICAL LABELING AND IMAGING, METHOD FOR PREPARING SAME SLC39A7, SLC30A7, SLC30A6 HTT 4012/4885ALDH1A1 1974/4885TDP1 2368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.