4-Phenoxyaniline

4-Phenoxyaniline

SCHEMBL159084

Nc1ccc(Oc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 1.00
ALDH1A1 P00352 5/20 0.78
TSHR P16473 2/20 0.78
TDP1 Q9NUW8 2/20 0.78
CYP3A4 P08684 1/20 0.78
MEN1 O00255 2/20 0.75
KMT2A Q03164 2/20 0.75
NPC1 O15118 1/20 0.75
RAB9A P51151 1/20 0.75
NLRP3 Q96P20 1/20 0.75
MAPT P10636 3/20 0.73
SMN1; SMN2 Q16637 3/20 0.73
MITF O75030 1/20 0.73
GAA P10253 1/20 0.73
GFER P55789 1/20 0.73
NLRP1 Q9C000 1/20 0.73
NOD2 Q9HC29 1/20 0.73
LTA4H P09960 3/20 0.67
MAOB P27338 2/20 0.62
TEAD4 Q15561 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL28089995 1.00 MAOA (1.00) MAOAALDH1A1TSHRTDP1CYP3A4
SCHEMBL554324 1.00 MAOA (1.00) MAOAALDH1A1TSHRTDP1CYP3A4
4-Phenoxyaniline SCHEMBL2830851 0.97 MAOA (0.95) MAOAALDH1A1TSHRTDP1CYP3A4
Benzene SCHEMBL28182432 0.94 MAOA (0.89) MAOAALDH1A1TSHRTDP1CYP3A4
SCHEMBL3786209 0.93 MAOA (0.86) MAOAALDH1A1TSHRTDP1CYP3A4
Benzidine SCHEMBL29023708 0.93 MAOA (0.86) MAOAALDH1A1TSHRTDP1CYP3A4
Diphenylether SCHEMBL27459833 0.92 MAOA (0.84) MAOAALDH1A1TSHRTDP1CYP3A4
SCHEMBL554191 0.91 ALDH1A1 (0.91) MAOAALDH1A1TSHRTDP1CYP3A4
Diphenylether SCHEMBL27923913 0.89 MAOA (0.80) MAOAALDH1A1TSHRTDP1CYP3A4
Ammonia Solution, Strong SCHEMBL562468 0.89 ALDH1A1 (0.87) MAOAALDH1A1TSHRTDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8674 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025481-A Photosensitive composite material for laser-assisted MicroLED mass transfer and preparation method and application thereof 厦门大学 2025-05-23 CN claimed
CN-117820129-B Method for preparing corresponding aromatic amine by selective hydrogenation of photocatalytic aromatic nitro compound 南京先进生物材料与过程装备研究院有限公司 2024-09-06 CN claimed
CN-118518884-A Functionalized magnetic microsphere and application thereof in troponin immunodetection 山东交通学院 2024-08-20 CN claimed
US-12054598-B2 Polymer aerogel with improved mechanical and thermal properties Blueshift Materials, Inc. (US) 2024-08-06 US claimed
CN-116789574-B Preparation method and application of camphorsulfonamide compound containing diphenyl ether group 南京林业大学 2024-07-30 CN claimed
CN-118344646-A Preparation method of shape memory fluorine-containing block polyimide aerogel with flexibility 江南大学 2024-07-16 CN claimed
CN-115723393-B Support body and application thereof 杭州福斯特应用材料股份有限公司 2024-07-16 CN claimed
CN-118344591-A Preparation method of thermosetting polyimide material using water as solvent 江苏海洋大学 2024-07-16 CN claimed
CN-118325081-A Cross-linked boron-containing high-temperature-resistant polyimide and preparation method thereof 合肥工业大学 2024-07-12 CN claimed
CN-118307778-A Extrusion type polyimide material, preparation method and application thereof 上海三普水相材料科技有限公司 2024-07-09 CN claimed
US-4940517-A Polymerization of aniline and its derivatives DREXEL UNIVERSITY (US) 1990-07-10 US claimed
EP-0315479-A2 Process for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-05-10 EP claimed
US-4720539-A Polyimide precursor compositions, their manufacture, the resultant polyimides and their use, particularly for manufacturing enamelling varnishes for electric wires CENTRE D'ETUDES DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1988-01-19 US claimed
US-4616053-A Hydrophobic polyamides BAYER AKTIENGESELLSCHAFT (DE) 1986-10-07 US claimed
EP-0186210-A2 Ion sensor TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1986-07-02 EP claimed
EP-0166321-A2 Hydrophobic polyamides BAYER AG (DE) 1986-01-02 EP claimed
US-4390596-A POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER RHONE-POULENC INDUSTRIES (FR) 1983-06-28 US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed
US-4225498-A Preparation of N-substituted oligo-imides RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US claimed
US-3939113-A ANTHRAQUINONE DYES CIBA-GEIGY CORPORATION (US) 1976-02-17 US claimed