Diphenylether

Diphenylether

SCHEMBL28089995

Nc1ccc(Oc2ccc(N)cc2)cc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 1.00
ALDH1A1 P00352 5/20 0.78
TSHR P16473 2/20 0.78
TDP1 Q9NUW8 2/20 0.78
CYP3A4 P08684 1/20 0.78
MEN1 O00255 2/20 0.75
KMT2A Q03164 2/20 0.75
NPC1 O15118 1/20 0.75
RAB9A P51151 1/20 0.75
NLRP3 Q96P20 1/20 0.75
MAPT P10636 3/20 0.73
SMN1; SMN2 Q16637 3/20 0.73
MITF O75030 1/20 0.73
GAA P10253 1/20 0.73
GFER P55789 1/20 0.73
NLRP1 Q9C000 1/20 0.73
NOD2 Q9HC29 1/20 0.73
LTA4H P09960 3/20 0.67
MAOB P27338 2/20 0.62
TEAD4 Q15561 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Phenoxyaniline SCHEMBL159084 1.00 MAOA (1.00) MAOAALDH1A1TSHRTDP1CYP3A4
SCHEMBL554324 1.00 MAOA (1.00) MAOAALDH1A1TSHRTDP1CYP3A4
4-Phenoxyaniline SCHEMBL2830851 0.97 MAOA (0.95) MAOAALDH1A1TSHRTDP1CYP3A4
Benzene SCHEMBL28182432 0.94 MAOA (0.89) MAOAALDH1A1TSHRTDP1CYP3A4
SCHEMBL3786209 0.93 MAOA (0.86) MAOAALDH1A1TSHRTDP1CYP3A4
Benzidine SCHEMBL29023708 0.93 MAOA (0.86) MAOAALDH1A1TSHRTDP1CYP3A4
Diphenylether SCHEMBL27459833 0.92 MAOA (0.84) MAOAALDH1A1TSHRTDP1CYP3A4
SCHEMBL554191 0.91 ALDH1A1 (0.91) MAOAALDH1A1TSHRTDP1CYP3A4
Diphenylether SCHEMBL27923913 0.89 MAOA (0.80) MAOAALDH1A1TSHRTDP1CYP3A4
Ammonia Solution, Strong SCHEMBL562468 0.89 ALDH1A1 (0.87) MAOAALDH1A1TSHRTDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117087276-A Viscoelastic polyurea waterproof coiled material and preparation method thereof 东营海瑞宝新材料有限公司 2023-11-21 CN claimed
CN-109913086-A High-strength ceramic powdery paints and its production technology 廊坊艾格玛新立材料科技有限公司 2019-06-21 CN claimed
CN-104262588-B A kind of epoxide resin conductive adhesive comprising graphite oxide thiazolinyl firming agent 湖南大学 2016-09-21 CN claimed
CN-117087276-A Viscoelastic polyurea waterproof coiled material and preparation method thereof 东营海瑞宝新材料有限公司 2023-11-21 CN disclosed
CN-109913086-A High-strength ceramic powdery paints and its production technology 廊坊艾格玛新立材料科技有限公司 2019-06-21 CN disclosed
CN-104262588-B A kind of epoxide resin conductive adhesive comprising graphite oxide thiazolinyl firming agent 湖南大学 2016-09-21 CN disclosed