SCHEMBL15908665

SCHEMBL15908665

c1ccc(-c2cc(-c3ccc4c(c3)C3(c5ccccc5-4)c4ccccc4-n4c5ccccc5c5cccc3c54)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.38
KMT2A Q03164 7/20 0.38
MAPT P10636 7/20 0.38
HPGD P15428 6/20 0.38
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 4/20 0.38
LMNA P02545 3/20 0.38
GLA P06280 1/20 0.38
NTSR1 P30989 1/20 0.36
DUSP3 P51452 1/20 0.33
MAOA P21397 3/20 0.32
MAOB P27338 3/20 0.32
PDK2 Q15119 2/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
CYP2C19 P33261 3/20 0.31
NPSR1 Q6W5P4 2/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21969898 0.99 MEN1 (0.37) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL15908630 0.98 MEN1 (0.36) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL15908626 0.97 MEN1 (0.35) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL15908620 0.97 MEN1 (0.35) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL15908655 0.97 MEN1 (0.35) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL21867774 0.96 MEN1 (0.34) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL22763820 0.96 MEN1 (0.34) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL15908625 0.95 MEN1 (0.34) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL15908656 0.94 MEN1 (0.39) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL15908666 0.94 DUSP3 (0.34) MEN1KMT2AMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200388767-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2020-12-10 US disclosed
US-20200388768-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2020-12-10 US disclosed
US-10461258-B2 Compound IDEMITSU KOSAN CO., LTD. (JP) 2019-10-29 US disclosed
US-20190006598-A1 NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-01-03 US disclosed
EP-2862862-B1 ORGANIC LIGHT EMITTING DEVICE COMPRISING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND LG CHEMICAL LTD (KR) 2019-01-02 EP disclosed
US-20170186968-A1 NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2017-06-29 US disclosed
US-20170186968-A1 NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2017-06-29 US disclosed
US-9203033-B2 Nitrogen-containing heterocyclic compounds and organic electronic device comprising the same LG CHEM, LTD. (KR) 2015-12-01 US disclosed
US-9203033-B2 Nitrogen-containing heterocyclic compounds and organic electronic device comprising the same LG CHEM, LTD. (KR) 2015-12-01 US disclosed
US-20140209884-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME LG CHEM LTD. (KR) 2014-07-31 US disclosed
US-20140209884-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME LG CHEM LTD. (KR) 2014-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190006598-A1 NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE PIEZO1, L1CAM, TMEM109 MEN1 587/4885KMT2A 2181/4885MAPT 1535/4885
US-10461258-B2 Compound CYP19A1, CYP17A1, CYP51A1 MEN1 202/4885KMT2A 1639/4885MAPT 3321/4885
US-20170186968-A1 NOVEL COMPOUND SREBF1, BRIX1, SREBF2 MEN1 2873/4885KMT2A 3156/4885MAPT 4190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.