SCHEMBL15909643

SCHEMBL15909643

CC1(C)c2cccc3ccc4cc(-c5ccc(N(c6ccc(C#N)cc6)c6cccnc6)c6ccccc56)cc1c4c23

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 6/20 0.34
CYP11B1 P15538 5/20 0.34
CYP17A1 P05093 1/20 0.34
CYP3A4 P08684 5/20 0.33
ABCG2 Q9UNQ0 1/20 0.31
GBA1 P04062 1/20 0.31
GRM5 P41594 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849672 0.88 PDK2 (0.35) CYP3A4ABCG2PDK2
SCHEMBL15909632 0.88 CA1 (0.32) ABCG2PDK2
SCHEMBL17849652 0.88 PIM1 (0.31) ABCG2PDK2
SCHEMBL15909642 0.86 PDK2 (0.34) PDK2
SCHEMBL15909649 0.86 FABP1 (0.39) PDK2
SCHEMBL15909639 0.85 CYP11B2 (0.39) CYP11B2CYP11B1CYP17A1CYP3A4GRM5
SCHEMBL15909788 0.84 CYP11B2 (0.41) CYP11B2CYP11B1CYP17A1CYP3A4ABCG2
SCHEMBL17849657 0.82 ABCG2 (0.36) ABCG2PDK2
SCHEMBL15909666 0.81 CYP11B2 (0.48) CYP11B2CYP11B1CYP17A1CYP3A4
SCHEMBL17849651 0.81 RXRA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140209872-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20140209872-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed