SCHEMBL17849672

SCHEMBL17849672

CC1(C)c2cccc3ccc4cc(-c5ccc(N(c6ccc(C#N)cc6)c6ccc(-c7ccccc7)cc6)c6ccccc56)cc1c4c23

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.35
PGR P06401 2/20 0.34
ABCG2 Q9UNQ0 2/20 0.34
GABRA1 P14867 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
KDM1A O60341 1/20 0.31
HRH3 Q9Y5N1 2/20 0.31
ABCB1 P08183 1/20 0.30
MYC P01106 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849657 0.94 ABCG2 (0.36) PDK2PGRABCG2GABRA1GABRG2
SCHEMBL15909632 0.93 CA1 (0.32) PDK2ABCG2
SCHEMBL17849652 0.93 PIM1 (0.31) PDK2ABCG2
SCHEMBL17849651 0.91 RXRA (0.31)
SCHEMBL15909642 0.91 PDK2 (0.34) PDK2PGR
SCHEMBL15909634 0.88 CA1 (0.34) PDK2PGRABCG2KDM1AHRH3
SCHEMBL15909667 0.88 CA1 (0.34) PDK2PGRABCG2KDM1AHRH3
SCHEMBL17849647 0.88 MYC (0.37) PDK2PGRABCG2GABRA1GABRG2
SCHEMBL15909643 0.88 CYP11B2 (0.34) PDK2ABCG2CYP3A4
SCHEMBL15909649 0.87 FABP1 (0.39) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed