Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11734829 | 0.95 | LMNA (0.40) | THRBLMNACA12CA1CA2 | |
| SCHEMBL15909718 | 0.93 | POLB (0.38) | THRBLMNACA12CA1CA2 | |
| SCHEMBL15909720 | 0.93 | POLB (0.41) | THRBLMNACA12CA1CA2 | |
| SCHEMBL15909727 | 0.88 | POLB (0.42) | THRBLMNACA12CA1CA2 | |
| SCHEMBL15909726 | 0.83 | LMNA (0.41) | THRBLMNACA12CA1CA2 | |
| SCHEMBL19145906 | 0.83 | LMNA (0.39) | LMNACA12CA1CA2CA3 | |
| SCHEMBL15909699 | 0.82 | TSHR (0.37) | THRBLMNACA12CA1CA2 | |
| SCHEMBL15909722 | 0.79 | TSHR (0.41) | LMNACA12CA1CA2CA3 | |
| SCHEMBL15909728 | 0.78 | LMNA (0.39) | LMNACA12CA1CA2CA3 | |
| SCHEMBL15909697 | 0.77 | LMNA (0.40) | THRBLMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751866-B2 | Hemi-aminal ethers and thioethers of N-alkenyl cyclic compounds | ISP INVESTMENTS LLC (US) | 2017-09-05 | — | — | US | disclosed |
| US-9751866-B2 | Hemi-aminal ethers and thioethers of N-alkenyl cyclic compounds | ISP INVESTMENTS LLC (US) | 2017-09-05 | — | — | US | disclosed |
| US-20150344461-A1 | HEMI-AMINAL ETHERS AND THIOETHERS OF N-ALKENYL CYCLIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2015-12-03 | — | — | US | disclosed |
| US-20150344461-A1 | HEMI-AMINAL ETHERS AND THIOETHERS OF N-ALKENYL CYCLIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2015-12-03 | — | — | US | disclosed |
| WO-2014116560-A1 | HEMI-AMINAL ETHERS AND THIOETHERS OF N-ALKENYL CYCLIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2014-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344461-A1 | HEMI-AMINAL ETHERS AND THIOETHERS OF N-ALKENYL CYCLIC COMPOUNDS | TST, AHR, ALOX12 | THRB 1133/4885LMNA 2026/4885CA12 4409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.