Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2689091 | 0.83 | CYP2A6 (0.49) | CYP3A4CYP2A6CYP2C19CYP2E1CYP2C9 | |
| SCHEMBL2691331 | 0.72 | CYP2A6 (0.50) | CYP3A4CYP2A6CYP2C19CYP2E1CYP2C9 | |
| SCHEMBL2689279 | 0.71 | CYP2A6 (0.51) | CYP3A4CYP2A6CYP2C19CYP2E1CYP2C9 | |
| SCHEMBL2688788 | 0.69 | VCP (0.49) | CYP3A4CYP2A6CYP2C19CYP2E1CYP2C9 | |
| SCHEMBL17980254 | 0.69 | MAPT (0.55) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL15656673 | 0.67 | MAPT (0.50) | CYP2C9F2ADORA2AADORA1CYP1A2 | |
| SCHEMBL17980295 | 0.66 | NAMPT (0.48) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL2690983 | 0.66 | GPR142 (0.50) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL17580398 | 0.66 | CYP2A6 (0.41) | CYP3A4CYP2A6CYP2C19CYP2E1CYP2C9 | |
| SCHEMBL5216349 | 0.65 | EPHX2 (0.54) | CYP3A4CYP2A6CYP2C19CYP2E1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213448-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213448-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | CYP3A4 129/4885CYP2A6 368/4885CYP2C19 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.