SCHEMBL15910553

SCHEMBL15910553

C=C(C)C(=O)OCCCOc1ccccc1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.57
▸ SMN1; SMN2 Q16637 5/20 0.57
▸ MTNR1A P48039 1/20 0.54
▸ MTNR1B P49286 1/20 0.54
▸ TDP1 Q9NUW8 3/20 0.49
▸ HTT P42858 3/20 0.49
▸ POLB P06746 2/20 0.49
▸ NPSR1 Q6W5P4 2/20 0.49
▸ APEX1 P27695 1/20 0.49
▸ L3MBTL1 Q9Y468 4/20 0.47
▸ MAPT P10636 4/20 0.47
▸ TSHR P16473 2/20 0.46
▸ NPC1 O15118 2/20 0.45
▸ RAB9A P51151 2/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ ADRB2 P07550 1/20 0.45
▸ HSP90AA1 P07900 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15910793 0.97 LMNA (0.61) LMNASMN1; SMN2MTNR1AMTNR1BTDP1
SCHEMBL15910565 0.95 LMNA (0.60) LMNASMN1; SMN2MTNR1AMTNR1BTDP1
SCHEMBL15910755 0.95 LMNA (0.60) LMNASMN1; SMN2MTNR1AMTNR1BTDP1
SCHEMBL8363546 0.92 NPSR1 (0.57) LMNASMN1; SMN2MTNR1AMTNR1BTDP1
SCHEMBL17036757 0.87 ALDH1A1 (0.53) LMNASMN1; SMN2MTNR1AMTNR1BTDP1
SCHEMBL15910699 0.87 SMN1; SMN2 (0.62) LMNASMN1; SMN2TDP1HTTPOLB
SCHEMBL10580556 0.85 THRB (0.50) LMNASMN1; SMN2MTNR1AMTNR1BTDP1
SCHEMBL10646027 0.85 GAA (0.51) LMNASMN1; SMN2TDP1HTTPOLB
SCHEMBL13328823 0.85 TDP1 (0.54) LMNATDP1HTTPOLBAPEX1
SCHEMBL15910690 0.84 SMN1; SMN2 (0.57) LMNASMN1; SMN2TDP1HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2762506-B1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION KANEKA CORP (JP) 2022-09-07 — — EP disclosed
US-9708424-B2 (Meth)acryloyl-terminated polyisobutylene polymer, method for producing the same, and active energy ray-curable composition KANEKA CORPORATION (JP) 2017-07-18 — — US disclosed
US-20170051093-A1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING THE SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION KANEKA CORP (JP) 2017-02-23 — — US disclosed
CN-103827158-B (meth)acryloyl-terminated polyisobutylene polymer, method for producing same, and active energy ray-curable composition 株式会社钟化 2017-02-15 — — CN disclosed
US-9512247-B2 (Meth)acryloyl-terminated polyisobutylene polymer, method for producing the same, and active energy ray-curable composition KANEKA CORPORATION (JP) 2016-12-06 — — US disclosed
US-20140243444-A1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING THE SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION KANEKA CORPORATION (JP) 2014-08-28 — — US disclosed
EP-2762506-A1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION Kaneka Corporation (JP) 2014-08-06 — — EP disclosed
CN-103827158-A (meth)acryloyl-terminated polyisobutylene polymer, method for producing same, and active energy ray-curable composition KANEKA CORP 2014-05-28 — — CN disclosed
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