SCHEMBL15911343

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1465773	0.79	MEN1 (0.54)	LMNAMAPTMEN1KMT2ANPSR1
	SCHEMBL349353	0.78	HDAC1 (0.42)	LMNAMAPTMEN1KMT2AHPGD
	SCHEMBL14712065	0.74	HRH3 (0.45)	MAPTALDH1A1SMN1; SMN2NPC1RAB9A
	SCHEMBL3227451	0.73	MEN1 (0.58)	LMNAMAPTMEN1KMT2ANPSR1
	SCHEMBL3052103	0.73	HDAC1 (0.47)	LMNAMAPTALDH1A1MAPK1SMN1; SMN2
	SCHEMBL3054538	0.73	HDAC1 (0.50)	LMNAMAPTMEN1KMT2AALDH1A1
	SCHEMBL3049424	0.72	HDAC1 (0.51)	LMNAMAPTALDH1A1MAPK1HTT
	SCHEMBL15054845	0.71	KDM1A (0.47)	LMNAMAPTMEN1KMT2AHPGD
	SCHEMBL14790321	0.71	OPRM1 (0.42)	LMNAMAPTMEN1KMT2ANPSR1
	SCHEMBL3903075	0.70	L3MBTL1 (0.58)	LMNAMAPTMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.