Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 3/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15911260 | 0.88 | WDR5 (0.36) | MAPTHCRTR2WDR5 | |
| SCHEMBL15911410 | 0.87 | SMO (0.35) | HCRTR2HCRTR1AOC3WDR5SMO | |
| SCHEMBL169439 | 0.78 | CXCR3 (0.52) | MAPTHCRTR2HCRTR1CXCR3KCNH2 | |
| SCHEMBL15911219 | 0.78 | MAPT (0.38) | MAPTHCRTR2HCRTR1AOC3WDR5 | |
| SCHEMBL15911272 | 0.77 | WDR5 (0.36) | WDR5SMOCXCR3KCNH2 | |
| SCHEMBL115607 | 0.74 | HTR1A (0.37) | MAPTKCNH2 | |
| SCHEMBL114031 | 0.72 | CXCR3 (0.35) | CXCR3 | |
| SCHEMBL165747 | 0.70 | CXCR3 (0.49) | HCRTR2HCRTR1CXCR3KCNH2 | |
| SCHEMBL165509 | 0.68 | CXCR3 (0.51) | CXCR3KCNH2 | |
| SCHEMBL114718 | 0.67 | CXCR3 (0.39) | AOC3SMOCXCR3KCNH2TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424840-B1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2014-08-06 | — | — | EP | disclosed |