Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | QDPR | P09417 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735267 | 0.93 | AKR1C1 (0.49) | HSD11B1CYP3A4SIGMAR1AKR1C1 | |
| SCHEMBL31045643 | 0.85 | CYP3A4 (0.56) | HSD11B1CYP3A4APPCYP2D6CYP2C9 | |
| SCHEMBL348524 | 0.82 | CYP3A4 (0.64) | HSD11B1CYP3A4APPCYP2D6CYP2C9 | |
| SCHEMBL31045651 | 0.82 | CYP3A4 (0.60) | HSD11B1CYP3A4APPCYP2D6CYP2C9 | |
| SCHEMBL9786867 | 0.76 | CYP3A4 (0.61) | HSD11B1CYP3A4APPCYP2D6CYP2C9 | |
| SCHEMBL1305458 | 0.76 | HDAC3 (0.55) | QDPRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3099869 | 0.75 | HSD11B1 (0.49) | HSD11B1CYP3A4APPCYP2D6CYP2C9 | |
| SCHEMBL17888245 | 0.74 | OPRM1 (0.64) | CYP2C19AKR1C1 | |
| Hydrochloric Acid SCHEMBL4652141 | 0.74 | KDM1A (0.54) | QDPRHDAC3HDAC4HDAC1HDAC7 | |
| Acetic Acid SCHEMBL29567593 | 0.74 | QDPR (0.56) | QDPRHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR5 | HSD11B1 2652/4885CYP3A4 4748/4885APP 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.