Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 19/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OXGR1 | Q96P68 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20481383 | 0.84 | SUCNR1 (0.50) | SUCNR1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL18626279 | 0.78 | SUCNR1 (0.43) | SUCNR1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL6563211 | 0.76 | SUCNR1 (0.61) | SUCNR1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL15154286 | 0.75 | PDE10A (0.40) | MEN1KMT2A | |
| SCHEMBL24193793 | 0.75 | SUCNR1 (0.57) | SUCNR1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL30471836 | 0.75 | SUCNR1 (0.57) | SUCNR1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL12463786 | 0.73 | KDM4E (0.54) | SUCNR1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL13719339 | 0.73 | SUCNR1 (0.58) | SUCNR1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL6129289 | 0.72 | KCNH2 (0.55) | SUCNR1OXGR1 | |
| SCHEMBL276117 | 0.72 | SUCNR1 (0.50) | SUCNR1KDM4EMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8901144-B2 | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives | SCIFLUOR LIFE SCIENCES, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| US-20140221410-A1 | Fluorinated 3-(2-Oxo-3-(3-Arylpropyl)Imidazolidin-1-yl)-3-Arylpropanoic Acid Derivatives | SCIFLUOR LIFE SCIENCES, LLC (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221410-A1 | Fluorinated 3-(2-Oxo-3-(3-Arylpropyl)Imidazolidin-1-yl)-3-Arylpropanoic Acid Derivatives | ITGB3, ITGA2, ITGA1 | SUCNR1 825/4885KDM4E 4092/4885MEN1 4448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.