Methacrylic Acid

Methacrylic Acid

SCHEMBL159154

C=C(C)C(=O)[O-].C=C(CCC[N+](C)(C)C)C(=O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.48
BBOX1 O75936 11/20 0.35
ENPP2 Q13822 3/20 0.32
APOBEC3A P31941 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
GALR3 O60755 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA1A P35348 1/20 0.31
PGR P06401 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
HTR1A P08908 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRM3 P20309 1/20 0.31
TBXA2R P21731 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL6561454 0.89 ACHE (0.52) ACHEBBOX1ENPP2APOBEC3AAPOBEC3G
Hydrochloric Acid SCHEMBL324011 0.87 ACHE (0.52) ACHEBBOX1ENPP2ADRA2AADRA1A
Hydrochloric Acid SCHEMBL2936558 0.87 ACHE (0.52) ACHEBBOX1ENPP2APOBEC3AAPOBEC3G
SCHEMBL170245 0.83 ACHE (0.52) ACHEBBOX1ENPP2APOBEC3AAPOBEC3G
Hydrochloric Acid SCHEMBL8448319 0.81 ACHE (0.50) ACHEBBOX1ENPP2APOBEC3AAPOBEC3G
Hydrochloric Acid SCHEMBL1703796 0.81 ACHE (0.45) ACHEBBOX1ENPP2APOBEC3AAPOBEC3G
Hydrochloric Acid SCHEMBL8222907 0.80 ACHE (0.45) ACHEBBOX1ENPP2APOBEC3AAPOBEC3G
Hydrochloric Acid SCHEMBL8695365 0.80 ACHE (0.45) ACHEBBOX1ENPP2APOBEC3AAPOBEC3G
Hydrochloric Acid SCHEMBL9497105 0.79 APEX1 (0.48) ACHEENPP2APOBEC3AAPOBEC3GSMN1; SMN2
SCHEMBL17456221 0.78 ACHE (0.40) ACHEBBOX1ENPP2ADRA2AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2523944-A1 COMPOUNDS AND COMPOSITIONS FOR COGNITION-ENHANCEMENT, METHODS OF MAKING, AND METHODS OF TREATING Mithridion, Inc. (US) 2012-11-21 EP disclosed
WO-2012030314-A1 COMPOSITIONS COMPRISING 5-(3-ETHYL-1,2,4-OXADIAZOL-5-YL)-1,4,5,6-TETRAHYDROPYRIMIDINE, AND METHODS OF ADMINISTERING SAME MITHRIDION, INC. (US) 2012-03-08 WO disclosed
EP-2403340-A1 COMPOUNDS AND COMPOSITIONS FOR COGNITION-ENHANCEMENT, METHODS OF MAKING, AND METHODS OF TREATING Mithridion, Inc. (US) 2012-01-11 EP disclosed
WO-2011085406-A1 COMPOUNDS AND COMPOSITIONS FOR COGNITION-ENHANCEMENT, METHODS OF MAKING, AND METHODS OF TREATING MITHRIDION, INC. (US) 2011-07-14 WO disclosed
WO-2010102218-A1 COMPOUNDS AND COMPOSITIONS FOR COGNITION-ENHANCEMENT, METHODS OF MAKING, AND METHODS OF TREATING MITHRIDION, INC. (US) 2010-09-10 WO disclosed