Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143708 | 0.98 | SIGMAR1 (0.65) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| SCHEMBL22899588 | 0.98 | SIGMAR1 (0.65) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL1331235 | 0.95 | SIGMAR1 (0.63) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| Bromide SCHEMBL1331742 | 0.95 | SIGMAR1 (0.63) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| Methyl Alcohol SCHEMBL29261100 | 0.93 | SIGMAR1 (0.61) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| Alcohol SCHEMBL9136417 | 0.89 | SIGMAR1 (0.57) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL3332713 | 0.87 | SIGMAR1 (0.55) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| Toluene SCHEMBL27514860 | 0.87 | SMN1; SMN2 (0.61) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| Putrescine SCHEMBL8006412 | 0.86 | SIGMAR1 (0.53) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| SCHEMBL22462469 | 0.86 | SIGMAR1 (0.53) | SIGMAR1POLBKDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102702007-A | Synthesis of 5-methoxyl-2-methylene-Nmethylformamide indene compounds | SHENGSHI TAIKE BIOMEDICAL TECHNOLOGY SUZHOU CO LTD | 2012-10-03 | — | — | CN | claimed |
| US-9051305-B2 | Compositions and methods useful for treating diseases | EUTROPICS PHARMACEUTICALS, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20140221387-A1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | EUTROPICS PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| CN-102702007-A | Synthesis of 5-methoxyl-2-methylene-Nmethylformamide indene compounds | SHENGSHI TAIKE BIOMEDICAL TECHNOLOGY SUZHOU CO LTD | 2012-10-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221387-A1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | BCL3, MCL1, BCL6 | SIGMAR1 4714/4885POLB 1677/4885KDM4E 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.