Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Phenyl-Butylamine SCHEMBL6853029 | 0.93 | MAOA (0.63) | SIGMAR1MAOA | |
| SCHEMBL22899588 | 0.88 | SIGMAR1 (0.65) | SIGMAR1POLBIDO1SMN1; SMN2CYP3A4 | |
| SCHEMBL143708 | 0.88 | SIGMAR1 (0.65) | SIGMAR1POLBIDO1SMN1; SMN2CYP3A4 | |
| Bromide SCHEMBL1331742 | 0.86 | SIGMAR1 (0.63) | SIGMAR1POLBIDO1SMN1; SMN2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL15917374 | 0.86 | SIGMAR1 (0.63) | SIGMAR1POLBIDO1SMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1331235 | 0.86 | SIGMAR1 (0.63) | SIGMAR1POLBIDO1SMN1; SMN2CYP3A4 | |
| Methyl Alcohol SCHEMBL29261100 | 0.84 | SIGMAR1 (0.61) | SIGMAR1POLBIDO1SMN1; SMN2CYP3A4 | |
| SCHEMBL5950278 | 0.83 | MAOA (0.46) | SIGMAR1MAOA | |
| Alcohol SCHEMBL9136417 | 0.80 | SIGMAR1 (0.57) | SIGMAR1POLBIDO1SMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL27850743 | 0.79 | SIGMAR1 (0.52) | SIGMAR1MAOATLR2POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |