Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143708 | 1.00 | SIGMAR1 (0.65) | SIGMAR1POLBCYP3A4MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL1331235 | 0.98 | SIGMAR1 (0.63) | SIGMAR1POLBCYP3A4MAPTKDM4E | |
| Bromide SCHEMBL1331742 | 0.98 | SIGMAR1 (0.63) | SIGMAR1POLBCYP3A4MAPTKDM4E | |
| Ammonia Solution, Strong SCHEMBL15917374 | 0.98 | SIGMAR1 (0.63) | SIGMAR1POLBCYP3A4MAPTKDM4E | |
| Methyl Alcohol SCHEMBL29261100 | 0.95 | SIGMAR1 (0.61) | SIGMAR1POLBCYP3A4MAPTKDM4E | |
| Alcohol SCHEMBL9136417 | 0.91 | SIGMAR1 (0.57) | SIGMAR1POLBCYP3A4MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL3332713 | 0.89 | SIGMAR1 (0.55) | SIGMAR1POLBCYP3A4MAPTKDM4E | |
| Toluene SCHEMBL27514860 | 0.89 | SMN1; SMN2 (0.61) | SIGMAR1POLBCYP3A4MAPTKDM4E | |
| Putrescine SCHEMBL8006412 | 0.88 | SIGMAR1 (0.53) | SIGMAR1POLBCYP3A4MAPTKDM4E | |
| SCHEMBL22462469 | 0.88 | SIGMAR1 (0.53) | SIGMAR1POLBCYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011689-A1 | CD73 INHIBITORS | ORIC PHARMACEUTICALS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |