Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102937 | 0.80 | TSHR (0.54) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL5597642 | 0.78 | TSHR (0.55) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL5597611 | 0.74 | TSHR (0.56) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL16047911 | 0.73 | TSHR (0.81) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL3862290 | 0.73 | TSHR (0.60) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL4735018 | 0.73 | TSHR (0.60) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL8455288 | 0.73 | ALDH1A1 (0.57) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL458513 | 0.72 | FOLH1 (0.47) | TSHRL3MBTL1TDP1CYP3A4TP53 | |
| SCHEMBL5317844 | 0.72 | TSHR (0.58) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| Hydrochloric Acid SCHEMBL6923875 | 0.72 | TSHR (0.58) | TSHRL3MBTL1TDP1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040751-B2 | Method for producing ring-halogenated N,N-dialkylbenzylamines | LANXESS DEUTSCHLAND GMBH (US) | 2015-05-26 | — | — | US | disclosed |
| US-20140221691-A1 | METHOD FOR PRODUCING RING-HALOGENATED N,N-DIALKYLBENZYLAMINES | LANXESS DEUTSCHLAND GMBH (DE) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221691-A1 | METHOD FOR PRODUCING RING-HALOGENATED N,N-DIALKYLBENZYLAMINES | NPM1, UGT1A6, NNMT | TSHR 1201/4885L3MBTL1 3681/4885TDP1 3662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.