Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | NPY2R | P49146 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919821 | 0.78 | NPSR1 (1.00) | ALDH1A1NPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL15919858 | 0.78 | ALDH1A1 (0.67) | ALDH1A1NPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL15919856 | 0.78 | ALDH1A1 (0.76) | ALDH1A1NPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL15919649 | 0.75 | KDM4E (0.85) | ALDH1A1NPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL15919820 | 0.75 | KMT2A (1.00) | ALDH1A1NPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL31681419 | 0.67 | CA2 (0.60) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL15919822 | 0.66 | MEN1 (0.78) | ALDH1A1NPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL6307904 | 0.66 | MAPT (0.66) | ALDH1A1NPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL15919823 | 0.66 | KDM4E (1.00) | ALDH1A1NPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL2616424 | 0.66 | METAP2 (0.63) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |