Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | NPY2R | P49146 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.70 |
| ▸ | LMNA | P02545 | 6/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919863 | 0.87 | MAPT (0.80) | MGLLMAPTNPY2RALDH1A1LMNA | |
| SCHEMBL19357237 | 0.87 | NPY2R (0.66) | MGLLMAPTNPY2RALDH1A1LMNA | |
| SCHEMBL14119792 | 0.85 | ALDH1A1 (0.82) | MAPTALDH1A1LMNAGAAL3MBTL1 | |
| SCHEMBL19357107 | 0.85 | MGLL (1.00) | MGLLMAPTNPY2RALDH1A1LMNA | |
| SCHEMBL15919867 | 0.85 | NPY2R (0.73) | MGLLMAPTNPY2RALDH1A1LMNA | |
| SCHEMBL15919866 | 0.84 | NPY2R (1.00) | MGLLMAPTNPY2RALDH1A1LMNA | |
| SCHEMBL7623077 | 0.81 | ALDH1A1 (0.76) | MAPTNPY2RALDH1A1LMNATDP1 | |
| SCHEMBL15920165 | 0.81 | CACNA2D1 (0.68) | MGLLMAPTALDH1A1HTTKMT2A | |
| SCHEMBL11179944 | 0.78 | ALDH1A1 (0.96) | MAPTALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL16227143 | 0.77 | ALDH1A1 (0.73) | MAPTALDH1A1LMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |