Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.68 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.68 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.68 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | CNR1 | P21554 | 2/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920269 | 0.91 | CA12 (0.64) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL15920168 | 0.90 | CACNA2D1 (0.61) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL15919857 | 0.87 | MAPT (0.70) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL15920162 | 0.87 | FAAH (0.60) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL10729724 | 0.85 | KDM4E (0.77) | KMT2ANPSR1HTTMEN1KDM4E | |
| SCHEMBL2897923 | 0.85 | KDM4E (0.77) | KMT2ANPSR1HTTMEN1KDM4E | |
| SCHEMBL15920167 | 0.85 | FAAH (0.64) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL18657820 | 0.84 | LMNA (0.63) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL15920163 | 0.84 | NPY2R (0.76) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL20328219 | 0.83 | KDM4E (0.65) | KDM4EMAPTCYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |