SCHEMBL1592019

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1591379	1.00	ALDH1A1 (0.42)	ALDH1A1SMN1; SMN2GAAHTTERN1
	SCHEMBL1591381	1.00	ALDH1A1 (0.42)	ALDH1A1SMN1; SMN2GAAHTTERN1
	SCHEMBL12703924	0.90	ALDH1A1 (0.41)	ALDH1A1SMN1; SMN2GAAHTTERN1
	SCHEMBL6103068	0.86	ERN1 (0.44)	ALDH1A1SMN1; SMN2HTTERN1HSD17B10
	SCHEMBL1591509	0.83	ERN1 (0.42)	ALDH1A1SMN1; SMN2ERN1HSD17B10KMT2A
	SCHEMBL12703547	0.83	ALDH1A1 (0.45)	ALDH1A1SMN1; SMN2GAAHTTKMT2A
	SCHEMBL29914789	0.83	ALDH1A1 (0.41)	ALDH1A1SMN1; SMN2ERN1KMT2AMEN1
	SCHEMBL27159784	0.83	ALDH1A1 (0.41)	ALDH1A1SMN1; SMN2ERN1KMT2AMEN1
	SCHEMBL27159780	0.83	ALDH1A1 (0.41)	ALDH1A1SMN1; SMN2ERN1KMT2AMEN1
	SCHEMBL13660146	0.83	ALDH1A1 (0.41)	ALDH1A1SMN1; SMN2ERN1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.