SCHEMBL15922796

SCHEMBL15922796

CCCCCC=CC1=CC2CCC1C2

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.33
FAAH O00519 3/20 0.32
MGLL Q99685 1/20 0.32
TRPV1 Q8NER1 5/20 0.32
CYP2C19 P33261 1/20 0.32
CNR1 P21554 4/20 0.31
CNR2 P34972 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15923385 0.98 ALDH1A1 (0.35) L3MBTL1ALDH1A1TSHRFAAHMGLL
SCHEMBL15922997 0.98 ALDH1A1 (0.35) L3MBTL1ALDH1A1TSHRFAAHMGLL
SCHEMBL2317331 0.95 L3MBTL1 (0.31) L3MBTL1
SCHEMBL1450946 0.82
SCHEMBL10544135 0.74 CNR1 (0.33) TRPV1CNR1CNR2
SCHEMBL4290581 0.72
SCHEMBL21866515 0.69 ALDH1A1 (0.34) L3MBTL1ALDH1A1TSHRFAAHMGLL
SCHEMBL649223 0.67 SPHK1 (0.41) ALDH1A1
SCHEMBL9500161 0.65 KDM4E (0.34)
SCHEMBL6046924 0.62 TNNC1 (0.55) ALDH1A1TSHRFAAHMGLLTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328126-B2 Norbornenylhydrocarbylene dihydrocarbylboranes and methods of making the same PROMERUS, LLC (US) 2016-05-03 US disclosed
US-20150353582-A1 NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME PROMERUS, LLC (US) 2015-12-10 US disclosed
WO-2014121008-A1 NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME PROMERUS, LLC (US) 2014-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150353582-A1 NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME CYP8B1, BDKRB1, CYP1B1 L3MBTL1 378/4885ALDH1A1 253/4885MEN1 116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.