Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15922888 | 1.00 | GRIN2D (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15922573 | 0.94 | EPHX2 (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15922575 | 0.94 | EPHX2 (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL17352351 | 0.92 | EPHX2 (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2803563 | 0.87 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL15937107 | 0.86 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1349916 | 0.81 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL4712177 | 0.79 | EPHX2 (0.39) | ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL4710638 | 0.79 | EPHX2 (0.39) | ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL6526108 | 0.77 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840465-B2 | Antiviral compounds | UNIV BRIGHAM YOUNG (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840465-B2 | Antiviral compounds | UNIV BRIGHAM YOUNG (US) | 2017-12-12 | — | — | US | disclosed |
| US-20150368196-A1 | ANTIVIRAL COMPOUNDS | UNIV BRIGHAM YOUNG (US) | 2015-12-24 | — | — | US | disclosed |
| US-20150368196-A1 | ANTIVIRAL COMPOUNDS | UNIV BRIGHAM YOUNG (US) | 2015-12-24 | — | — | US | disclosed |
| EP-2950789-A2 | ANTIVIRAL COMPOUNDS | Brigham Young University (US) | 2015-12-09 | — | — | EP | disclosed |
| WO-2014121170-A2 | ANTIVIRAL COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2014-08-07 | — | — | WO | disclosed |
| WO-2014121170-A2 | ANTIVIRAL COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2014-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368196-A1 | ANTIVIRAL COMPOUNDS | ACE, ADA, MAVS | GRIN2D 4607/4885GRIN3B 3613/4885GRIN1 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.