Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1349916 | 0.94 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2EPHX2GAA | |
| SCHEMBL4712177 | 0.92 | EPHX2 (0.39) | ALDH1A1SMN1; SMN2EPHX2GAA | |
| SCHEMBL4710638 | 0.92 | EPHX2 (0.39) | ALDH1A1SMN1; SMN2EPHX2GAA | |
| SCHEMBL15922888 | 0.87 | GRIN2D (0.31) | ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL15922889 | 0.87 | GRIN2D (0.31) | ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL4712185 | 0.86 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15923054 | 0.86 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29078826 | 0.84 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15922573 | 0.81 | EPHX2 (0.33) | EPHX2 | |
| SCHEMBL15922575 | 0.81 | EPHX2 (0.33) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789600-A | Preparation method and application of novel tetrahydroindazole antitumor compound | 深圳市人民医院 | 2023-09-22 | — | — | CN | claimed |
| CN-116444438-B | Benzamide compound and preparation method, using method and application thereof | 深圳市人民医院 | 2024-02-13 | — | — | CN | disclosed |
| CN-116789600-A | Preparation method and application of novel tetrahydroindazole antitumor compound | 深圳市人民医院 | 2023-09-22 | — | — | CN | disclosed |
| CN-116444438-A | Benzamide compound and preparation method, using method and application thereof | 深圳市人民医院 | 2023-07-18 | — | — | CN | disclosed |
| US-20180022752-A1 | FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20140205947-A1 | PATTERN FORMING METHOD, CHEMICAL AMPLIFICATION RESIST COMPOSITION AND RESIST FILM | FUJIFILM CORPORATION (JP) | 2014-07-24 | — | — | US | disclosed |
| US-20140205947-A1 | PATTERN FORMING METHOD, CHEMICAL AMPLIFICATION RESIST COMPOSITION AND RESIST FILM | FUJIFILM CORPORATION (JP) | 2014-07-24 | — | — | US | disclosed |
| EP-1637514-B1 | METHOD FOR PRODUCING FLUORINE-CONTAINING ACRYLATE | TOSOH F TECH INC (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-7781131-B2 | Positive photosensitive resin composition, cured layer , protecting layer, insulating layer and semiconductor device and display therewith | SUMITOMO BAKELITE CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20090068584-A1 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, CURED LAYER, PROTECTING LAYER, INSULATING LAYER AND SEMICONDUCTOR DEVICE AND DISPLAY THEREWITH | SUMITOMO BAKELITE CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20030158437-A1 | Processes for preparation of 2-alkyl-2adamantyl esters | TOKUYAMA CORPORATION (JP) | 2003-08-21 | — | — | US | disclosed |
| US-20030135068-A1 | Process for preparation of high-purity organic compounds | TAKUYAMA CORPORATION (JP) | 2003-07-17 | — | — | US | disclosed |
| EP-1314713-A1 | PROCESSES FOR PREPARATION OF 2-ALKYL-2-ADAMANTYL ESTERS | TOKUYAMA CORPORATION (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6531511-B1 | N-methyl aspartate receptor antagonist | VERNALIS RESEARCH LIMITED (GB) | 2003-03-11 | — | — | US | disclosed |
| EP-1284252-A1 | PROCESS FOR PREPARATION OF HIGH-PURITY ORGANIC COMPOUNDS | TOKUYAMA CORPORATION (JP) | 2003-02-19 | — | — | EP | disclosed |
| EP-1143964-A1 | 2-ADAMANTANEMETHANAMINE COMPOUNDS FOR TREATING ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2001-10-17 | — | — | EP | disclosed |
| US-6248920-B1 | REACTING AN ALDEHYDE OR KETONE COMPOUND AND AN ACID HALIDE COMPOUND IN A ONE POT REACTION IN THE PRESENCE OF AN ORGANOMETALLIC COMPOUND TO DIRECTLY FORM THE ESTERS WITHOUT FORMING AN INTERMEDIATE ALCOHOL | FUJITSU LIMITED (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6174646-B1 | IMAGEWISE HEATING OR EXPOSING IMAGE FORMING MATERIAL TO LASER WHEREIN IMAGE FORMING MATERIAL COMPRISES SUPPORT HAVING RADIATION SENSITIVE LAYER CONTAINING DYE, AN ACID GENERATING COMPOUND CAPABLE OF GENERATING ACID ON IRRADIATION | KONICA CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| WO-2000044371-A1 | 2-ADAMANTANEMETHANAMINE COMPOUNDS FOR TREATING ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2000-08-03 | — | — | WO | disclosed |
| EP-0911153-A1 | Image forming method | KONICA CORPORATION (JP) | 1999-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022752-A1 | FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF | IDO1, IDO2, TDO2 | ALDH1A1 2128/4885SMN1; SMN2 3655/4885EPHX2 1124/4885 |
| US-20030158437-A1 | Processes for preparation of 2-alkyl-2adamantyl esters | ADSL, GRIN2D, SLC43A1 | ALDH1A1 403/4885SMN1; SMN2 1592/4885EPHX2 891/4885 |
| US-20030135068-A1 | Process for preparation of high-purity organic compounds | ALKBH5, MSMO1, MEP1B | ALDH1A1 410/4885SMN1; SMN2 796/4885EPHX2 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.