SCHEMBL15923946

SCHEMBL15923946

CC(C)c1cccc(C(C)C)c1N1CCCN(c2c(C(C)C)cccc2C(C)C)C1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALOX15 P16050 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 2/20 0.37
FAAH O00519 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
GABRA1 P14867 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
PTGS1 P23219 1/20 0.37
SLC6A2 P23975 1/20 0.37
HTR2C P28335 1/20 0.37
GABRB3 P28472 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1918403 0.93 ALOX15 (0.41) KMT2AMEN1TDP1ALOX15LMNA
SCHEMBL16678671 0.84 ALOX15 (0.40) KMT2AMEN1TDP1ALOX15LMNA
SCHEMBL27908721 0.81 ALDH1A1 (0.37) KMT2AMEN1TDP1ALOX15LMNA
SCHEMBL16678672 0.79 ALOX15 (0.37) KMT2AMEN1TDP1ALOX15LMNA
SCHEMBL16678737 0.75 ALOX15 (0.36) KMT2AMEN1TDP1ALOX15LMNA
SCHEMBL1917017 0.75 GABRA1 (0.41) KMT2AALOX15LMNAFAAHCA1
SCHEMBL15923852 0.70 MAPT (0.44) KMT2AMEN1TDP1L3MBTL1CYP3A4
SCHEMBL13698771 0.70 GABRA1 (0.41) KMT2AMEN1TDP1ALOX15LMNA
SCHEMBL22096053 0.69 DPP4 (0.40) KMT2AMEN1TDP1ALOX15LMNA
SCHEMBL27908724 0.69 ALDH1A1 (0.34) KMT2AMEN1TDP1ALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2999730-B1 POLYMERIZABLE REACTION MIXTURE FOR PRODUCING EPOXY RESINS, AND THE USE THEREOF DEUTSCHE INST FUER TEXTIL UND FASERFORSCHUNG DENKENDORF (DE) 2020-04-15 EP disclosed
US-20170218121-A2 RING-OPENING LAUROLACTAM POLYMERIZATION WITH LATENT INITIATORS EVONIK DEGUSSA GMBH (DE) 2017-08-03 US disclosed
US-20160137774-A1 LACTONE POLYMERIZATION WITH LATENT INITIATORS EVONIK DEGUSSA GMBH (DE) 2016-05-19 US disclosed
EP-2999730-A1 POLYMERIZABLE REACTION MIXTURE FOR PRODUCING EPOXY RESINS, AND THE USE THEREOF Deutsche Institute für Textil- und Faserforschung Denkendorf (DE) 2016-03-30 EP disclosed
EP-2951227-A1 METHOD FOR POLYMERIZING -CAPROLACTAM Evonik Industries AG (DE) 2015-12-09 EP disclosed
US-20150126696-A1 POLYMERIZATION USING LATENT INITIATORS EVONIK INDUSTRIES AG (DE) 2015-05-07 US disclosed
WO-2014118076-A1 METHOD FOR POLYMERIZING Ε-CAPROLACTAM EVONIK INDUSTRIES AG (DE) 2014-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160137774-A1 LACTONE POLYMERIZATION WITH LATENT INITIATORS HACD2, MCCC2, CWC22 KMT2A 2087/4885MEN1 2433/4885TDP1 4850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.