Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17188020 | 0.81 | NR4A1 (0.48) | MYCNR4A1TSHRCASP1SMN1; SMN2 | |
| SCHEMBL11486974 | 0.79 | KDM4E (0.41) | MAP4K4NPC1MAPTNFKB1RAB9A | |
| SCHEMBL1922976 | 0.76 | MYC (0.51) | MYCNR4A1TSHRCASP1SMN1; SMN2 | |
| SCHEMBL21934939 | 0.76 | MEN1 (0.60) | MYCNR4A1HPGDSALKBH2NPC1 | |
| SCHEMBL5064593 | 0.76 | AVPR2 (0.55) | MYCNR4A1TSHRCASP1SMN1; SMN2 | |
| SCHEMBL11486255 | 0.74 | NPC1 (0.43) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL2857156 | 0.74 | HPGDS (0.61) | TSHRHPGDSALKBH2 | |
| SCHEMBL4708591 | 0.73 | MYC (0.51) | MYCNR4A1TSHRCASP1SMN1; SMN2 | |
| SCHEMBL13097275 | 0.72 | MAP4K4 (0.39) | SMN1; SMN2MAP4K4PLAUELANENPC1 | |
| SCHEMBL11493968 | 0.72 | MAP4K4 (0.54) | MAP4K4HPGDSALKBH2PLAUELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161858-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200247828-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2020-08-06 | — | — | US | disclosed |
| US-10669291-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| US-20190135837-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2019-05-09 | — | — | US | disclosed |
| US-20180065994-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2018-03-08 | — | — | US | disclosed |
| US-9815857-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-20170210762-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2017-07-27 | — | — | US | disclosed |
| US-9598443-B2 | Boron containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150361104-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2015-12-17 | — | — | US | disclosed |
| WO-2014121124-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247828-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | MYC 2241/4885NR4A1 4097/4885TSHR 4354/4885 |
| US-11161858-B2 | Boron-containing small molecules as antiprotozoal agents | BTD, BAD, BRI3BP | MYC 2241/4885NR4A1 4097/4885TSHR 4354/4885 |
| US-20180065994-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | MYC 2241/4885NR4A1 4097/4885TSHR 4354/4885 |
| US-20190135837-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | MYC 2241/4885NR4A1 4097/4885TSHR 4354/4885 |
| US-10669291-B2 | Boron-containing small molecules as antiprotozoal agents | BTD, BAD, BRI3BP | MYC 2241/4885NR4A1 4097/4885TSHR 4354/4885 |
| US-20150361104-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | MYC 2241/4885NR4A1 4097/4885TSHR 4354/4885 |
| US-20170210762-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | MYC 2241/4885NR4A1 4097/4885TSHR 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.