Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11486184 | 0.83 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL11489095 | 0.83 | GRM4 (0.36) | NPC1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL6275209 | 0.78 | RAB9A (0.44) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL11485070 | 0.77 | CYP3A4 (0.37) | SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL182401 | 0.76 | MAP4K4 (0.53) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3422378 | 0.76 | RXRA (0.48) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL13097351 | 0.75 | DRD2 (0.39) | SMN1; SMN2MEN1KMT2ATP53LMNA | |
| SCHEMBL27834563 | 0.75 | MAP4K4 (0.54) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL15924522 | 0.74 | MYC (0.51) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL31517549 | 0.74 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239901-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-12-16 | — | — | US | disclosed |