Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 19/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 18/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 18/20 | 0.55 |
| ▸ | F10 | P00742 | 12/20 | 0.55 |
| ▸ | F2 | P00734 | 16/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48885 | 0.86 | CA2 (0.52) | F10SCN9A | |
| Acetic Acid SCHEMBL6695169 | 0.84 | SCN9A (0.50) | PRSS1PRSS2PRSS3F10F2 | |
| Hydrochloric Acid SCHEMBL6399557 | 0.84 | CA2 (0.50) | F10SCN9A | |
| Methane SCHEMBL27503773 | 0.84 | CA2 (0.50) | F10SCN9A | |
| Formic Acid SCHEMBL6028133 | 0.81 | CASP1 (0.49) | PRSS1PRSS2PRSS3F10SCN9A | |
| SCHEMBL27842438 | 0.80 | CA1 (0.54) | F10SCN9A | |
| SCHEMBL8350056 | 0.80 | CA1 (0.54) | SCN9A | |
| Trifluoroacetic Acid SCHEMBL27848730 | 0.79 | CA2 (0.45) | — | |
| Trimethylammonium SCHEMBL27979852 | 0.79 | CA2 (0.45) | F10SCN9A | |
| SCHEMBL8659843 | 0.78 | CA2 (0.48) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951170-A2 | FLAP MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2015-12-09 | — | — | EP | claimed |
| WO-2014121055-A2 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-07 | — | — | WO | claimed |