Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 6/20 | 0.42 |
| ▸ | FGF1 | P05230 | 2/20 | 0.39 |
| ▸ | AMY2A | P04746 | 1/20 | 0.37 |
| ▸ | SERPINC1 | P01008 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.34 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.34 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.34 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360872 | 1.00 | LGALS8 (0.42) | LGALS8FGF1AMY2ASERPINC1MGAM | |
| SCHEMBL22460849 | 1.00 | LGALS8 (0.42) | LGALS8FGF1AMY2ASERPINC1MGAM | |
| SCHEMBL12013749 | 1.00 | LGALS8 (0.42) | LGALS8FGF1AMY2ASERPINC1MGAM | |
| SCHEMBL7151354 | 1.00 | LGALS8 (0.42) | LGALS8FGF1AMY2ASERPINC1MGAM | |
| SCHEMBL7154448 | 1.00 | LGALS8 (0.42) | LGALS8FGF1AMY2ASERPINC1MGAM | |
| SCHEMBL313178 | 1.00 | LGALS8 (0.42) | LGALS8FGF1AMY2ASERPINC1MGAM | |
| SCHEMBL18343942 | 1.00 | LGALS8 (0.42) | LGALS8FGF1AMY2ASERPINC1MGAM | |
| SCHEMBL19425947 | 0.87 | LGALS8 (0.38) | LGALS8FGF1AMY2ASERPINC1LGALS3 | |
| SCHEMBL17986845 | 0.85 | L3MBTL1 (0.37) | LGALS8FGF1AMY2ASERPINC1MGAM | |
| SCHEMBL3903836 | 0.84 | LGALS8 (0.37) | LGALS8AMY2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217577-B1 | NOVEL COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES INC (US) | 2014-08-06 | — | — | EP | disclosed |