SCHEMBL22460849

SCHEMBL22460849

CO[C@H]1O[C@H](CO)[C@@H](OC)[C@H](OC)[C@H]1OC

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 6/20 0.42
▸ FGF1 P05230 2/20 0.39
▸ AMY2A P04746 1/20 0.37
▸ SERPINC1 P01008 1/20 0.36
▸ MGAM O43451 2/20 0.34
▸ SI P14410 2/20 0.34
▸ LGALS3 P17931 2/20 0.34
▸ LGALS9 O00182 1/20 0.34
▸ LGALS1 P09382 1/20 0.34
▸ LGALS7; LGALS7B P47929 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10360872 1.00 LGALS8 (0.42) LGALS8FGF1AMY2ASERPINC1MGAM
SCHEMBL12013749 1.00 LGALS8 (0.42) LGALS8FGF1AMY2ASERPINC1MGAM
SCHEMBL7151354 1.00 LGALS8 (0.42) LGALS8FGF1AMY2ASERPINC1MGAM
SCHEMBL7154448 1.00 LGALS8 (0.42) LGALS8FGF1AMY2ASERPINC1MGAM
SCHEMBL313178 1.00 LGALS8 (0.42) LGALS8FGF1AMY2ASERPINC1MGAM
SCHEMBL18343942 1.00 LGALS8 (0.42) LGALS8FGF1AMY2ASERPINC1MGAM
SCHEMBL15925201 1.00 LGALS8 (0.42) LGALS8FGF1AMY2ASERPINC1MGAM
SCHEMBL19425947 0.87 LGALS8 (0.38) LGALS8FGF1AMY2ASERPINC1LGALS3
SCHEMBL17986845 0.85 L3MBTL1 (0.37) LGALS8FGF1AMY2ASERPINC1MGAM
SCHEMBL3903836 0.84 LGALS8 (0.37) LGALS8AMY2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708320-B2 Environmentally-friendly hydroazidation of olefins GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-07-25 — — US disclosed
US-11203588-B2 Anti-cancer and splice modulating compounds and methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-12-21 — — US disclosed
US-20210284601-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-09-16 — — US disclosed
EP-3784660-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS Georgia State University Research Foundation, Inc. (US) 2021-03-03 — — EP disclosed
US-20200299279-A1 ANTI-CANCER AND SPLICE MODULATING COMPOUNDS AND METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-09-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200299279-A1 ANTI-CANCER AND SPLICE MODULATING COMPOUNDS AND METHODS SNRPA1, SNRPE, RBM17 LGALS8 1992/4885FGF1 4630/4885AMY2A 3735/4885
US-11203588-B2 Anti-cancer and splice modulating compounds and methods SNRPA1, SNRPE, RBM17 LGALS8 1992/4885FGF1 4630/4885AMY2A 3735/4885
US-11708320-B2 Environmentally-friendly hydroazidation of olefins HAO2, AHR, HMOX1 LGALS8 1783/4885FGF1 3991/4885AMY2A 2563/4885
US-20210284601-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS HAO2, AHR, HMOX1 LGALS8 1783/4885FGF1 3991/4885AMY2A 2563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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