Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 12/20 | 0.54 |
| ▸ | NOS2 | P35228 | 12/20 | 0.54 |
| ▸ | NOS3 | P29474 | 9/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15925898 | 0.78 | NOS1 (0.48) | NOS1NOS2NOS3 | |
| SCHEMBL3615141 | 0.74 | TAAR1 (0.67) | — | |
| SCHEMBL3615139 | 0.74 | TAAR1 (0.67) | — | |
| SCHEMBL16191333 | 0.73 | ALDH1A1 (0.46) | — | |
| SCHEMBL8200215 | 0.73 | NOS1 (0.46) | NOS1NOS2NOS3 | |
| SCHEMBL15399734 | 0.71 | SLC6A2 (0.39) | — | |
| SCHEMBL15400565 | 0.70 | SLC6A2 (0.41) | — | |
| SCHEMBL21581480 | 0.70 | SLC6A2 (0.41) | — | |
| SCHEMBL15399768 | 0.70 | DAO (0.39) | — | |
| SCHEMBL8767290 | 0.70 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114906-B1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS FOR CNS DISORDERS | HOFFMANN LA ROCHE (CH) | 2014-08-06 | — | — | EP | disclosed |