Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 11/20 | 0.48 |
| ▸ | NOS2 | P35228 | 10/20 | 0.48 |
| ▸ | NOS3 | P29474 | 7/20 | 0.48 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15925910 | 0.78 | NOS1 (0.54) | NOS1NOS2NOS3 | |
| SCHEMBL3607332 | 0.74 | — | — | |
| SCHEMBL3607329 | 0.74 | — | — | |
| SCHEMBL16191075 | 0.73 | HTR2A (0.58) | HTR2AHTR2C | |
| SCHEMBL8202601 | 0.71 | LOXL2 (0.45) | NOS1NOS2NOS3 | |
| SCHEMBL8200215 | 0.71 | NOS1 (0.46) | NOS1NOS2NOS3 | |
| SCHEMBL8153366 | 0.68 | HTR2A (0.56) | HTR2AHTR2C | |
| SCHEMBL8147279 | 0.68 | HTR2A (0.56) | HTR2AHTR2C | |
| SCHEMBL8148467 | 0.68 | HTR2A (0.56) | HTR2AHTR2C | |
| SCHEMBL22201819 | 0.68 | HTR2A (0.52) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114906-B1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS FOR CNS DISORDERS | HOFFMANN LA ROCHE (CH) | 2014-08-06 | — | — | EP | disclosed |