Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | FPR2 | P25090 | 2/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075693 | 0.89 | PKM (0.86) | PKMSMN1; SMN2RAB9ANPC1TAS1R3 | |
| SCHEMBL20415806 | 0.83 | PKM (0.68) | PKMSMN1; SMN2RAB9ANPC1SAE1 | |
| SCHEMBL20415917 | 0.81 | FPR2 (0.64) | PKMNPC1SAE1UBA2KMT2A | |
| SCHEMBL3063854 | 0.80 | PKM (0.66) | PKMSMN1; SMN2RAB9ANPC1SAE1 | |
| SCHEMBL13754509 | 0.80 | PKM (0.66) | PKMSMN1; SMN2RAB9ANPC1SAE1 | |
| SCHEMBL6016077 | 0.78 | MAPK1 (0.56) | PKMTAS1R3TAS1R1KMT2AMEN1 | |
| SCHEMBL18262738 | 0.78 | FPR2 (0.74) | PKMSMN1; SMN2RAB9ANPC1SAE1 | |
| SCHEMBL18262740 | 0.78 | FPR2 (0.74) | PKMSMN1; SMN2RAB9ANPC1SAE1 | |
| SCHEMBL20397813 | 0.78 | PKM (0.60) | PKMSMN1; SMN2RAB9ANPC1SAE1 | |
| SCHEMBL20397641 | 0.78 | PKM (0.60) | PKMSMN1; SMN2RAB9ANPC1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796272-B2 | Glycine transporter-inhibiting substances | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2014-08-05 | — | — | US | disclosed |
| US-8796272-B2 | Glycine transporter-inhibiting substances | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2014-08-05 | — | — | US | disclosed |