SCHEMBL20415917

SCHEMBL20415917

COc1ccc(CC[C@H](CO)NC(=O)Nc2ccc(Cl)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 4/20 0.64
CNR1 P21554 2/20 0.63
FPR1 P21462 1/20 0.58
PKM P14618 1/20 0.57
UTS2R Q9UKP6 1/20 0.55
SAE1 Q9UBE0 1/20 0.51
UBA2 Q9UBT2 1/20 0.51
KMT2A Q03164 4/20 0.50
KLK7 P49862 4/20 0.50
MEN1 O00255 3/20 0.50
NPC1 O15118 1/20 0.50
ALDH1A1 P00352 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
EPHX2 P34913 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18262740 0.88 FPR2 (0.74) FPR2CNR1FPR1PKMUTS2R
SCHEMBL20397782 0.88 FPR2 (0.74) FPR2CNR1FPR1PKMUTS2R
SCHEMBL18262738 0.88 FPR2 (0.74) FPR2CNR1FPR1PKMUTS2R
SCHEMBL20415806 0.81 PKM (0.68) FPR2FPR1PKMSAE1UBA2
SCHEMBL15925980 0.81 PKM (0.72) FPR2PKMUTS2RSAE1UBA2
SCHEMBL22753565 0.80 FPR2 (0.68) FPR2CNR1FPR1PKMUTS2R
SCHEMBL3075693 0.79 PKM (0.86) FPR2PKMSAE1UBA2KMT2A
SCHEMBL20415839 0.78 CNR1 (0.64) FPR2CNR1FPR1PKMUTS2R
SCHEMBL22723032 0.78 FPR2 (0.65) FPR2CNR1FPR1PKMUTS2R
SCHEMBL16562291 0.78 CNR1 (1.00) FPR2CNR1NPC1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10858314-B2 Urea derivative or pharmacologically acceptable salt thereof KYORIN PHARMACEUTICAL CO., LTD. (JP) 2020-12-08 US disclosed
US-20180208552-A1 UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF KYORIN PHARMACEUTICAL CO., LTD. (JP) 2018-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10858314-B2 Urea derivative or pharmacologically acceptable salt thereof FPR1, SAAL1, FPR2 FPR2 3/4885CNR1 338/4885FPR1 1/4885
US-20180208552-A1 UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF FPR1, FPR2, SAAL1 FPR2 2/4885CNR1 318/4885FPR1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.