Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ARF6 | P62330 | 6/20 | 0.40 |
| ▸ | PSD | A5PKW4 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1279349 | 0.90 | MEN1 (0.43) | PLATMEN1KMT2ANPSR1GAA | |
| SCHEMBL15926266 | 0.89 | MEN1 (0.35) | PLATMEN1KMT2ANPSR1GAA | |
| SCHEMBL1614861 | 0.85 | ARF6 (0.39) | PLATMEN1KMT2ANPSR1GAA | |
| SCHEMBL15926365 | 0.84 | ARF6 (0.36) | PLATMEN1KMT2ANPSR1GAA | |
| SCHEMBL15926321 | 0.84 | MAPK14 (0.40) | MEN1KMT2ANPSR1ARF6MAPT | |
| SCHEMBL15926267 | 0.83 | ALOX5 (0.43) | MEN1KMT2ANPSR1GAAARF6 | |
| SCHEMBL15909266 | 0.82 | ARF6 (0.39) | PLATMEN1KMT2ANPSR1ARF6 | |
| SCHEMBL1279260 | 0.82 | ARF6 (0.45) | PLATMEN1KMT2AARF6PSD | |
| SCHEMBL1279253 | 0.82 | PLAT (0.41) | PLATMEN1KMT2ANPSR1GAA | |
| SCHEMBL13516240 | 0.80 | PLAT (0.42) | PLATMEN1KMT2AARF6PSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796285-B2 | Pyrazolo [1,5-a]-pyrimidones derivatives and pharmaceutical compositions and uses thereof | HEBEI MEDICAL UNIVERSITY (CN) | 2014-08-05 | — | — | US | disclosed |