SCHEMBL1592944

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23872051	0.92	TP53 (0.38)	TP53IRAK4OPRM1OPRD1OGFRL1
	SCHEMBL1592421	0.92	CA12 (0.41)	CA12CA1CA2CA4CA5A
	SCHEMBL1592947	0.91	FPR2 (0.40)	TP53IRAK4FPR2OPRM1OPRD1
	SCHEMBL3633036	0.89	TRPV6 (0.36)	TP53
	SCHEMBL21556286	0.85	DDR1 (0.40)	—
	SCHEMBL1592454	0.84	DNMT3A (0.41)	FPR2USP30BACE1NSD2DNMT3A
	SCHEMBL13906846	0.84	IRAK4 (0.40)	TP53IRAK4FPR2OPRM1OPRD1
	SCHEMBL8403018	0.83	CA12 (0.37)	CA12CA1CA2CA4CA5A
	SCHEMBL8126846	0.83	IDO1 (0.38)	CA12CA1CA2CA4CA5A
	SCHEMBL8135777	0.83	CA12 (0.41)	CA12CA1CA2CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.