SCHEMBL15929631

SCHEMBL15929631

Sc1ccc(Oc2ccc(Oc3ccc(S)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
KMT2A Q03164 3/20 0.47
TSHR P16473 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
MEN1 O00255 2/20 0.47
CYP3A4 P08684 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
LTA4H P09960 4/20 0.44
IDO1 P14902 1/20 0.42
MAOA P21397 2/20 0.39
NR1H2 P55055 1/20 0.39
BAX Q07812 1/20 0.39
MAPT P10636 4/20 0.38
PARP15 Q460N3 1/20 0.38
PARP14 Q460N5 1/20 0.38
PARP10 Q53GL7 1/20 0.38
PARP16 Q8N5Y8 1/20 0.38
PARP11 Q9NR21 1/20 0.38
PARP4 Q9UKK3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9294674 1.00 ALDH1A1 (0.47) ALDH1A1KMT2ATSHRTDP1MEN1
SCHEMBL636168 1.00 ALDH1A1 (0.47) ALDH1A1KMT2ATSHRTDP1MEN1
SCHEMBL8826928 0.91 ALDH1A1 (0.41) ALDH1A1KMT2ATSHRTDP1MEN1
SCHEMBL487535 0.88 LTA4H (0.67) KMT2ATSHRMEN1LTA4HMAOA
SCHEMBL24495189 0.86 TEAD4 (0.58) ALDH1A1KMT2ATSHRTDP1MEN1
SCHEMBL13852701 0.86 TEAD4 (0.58) ALDH1A1KMT2ATSHRTDP1MEN1
SCHEMBL17416086 0.86 LTA4H (0.63) KMT2ATSHRMEN1LTA4HMAOA
SCHEMBL6236673 0.86 MEN1 (0.74) ALDH1A1KMT2AMEN1CYP3A4ESR1
SCHEMBL2329472 0.86 ALDH1A1 (0.74) ALDH1A1KMT2ATSHRTDP1MEN1
SCHEMBL2408044 0.86 IDO1 (0.68) ALDH1A1KMT2AMEN1LTA4HIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240052103-A1 POLYMER AND TRIAZINE COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-15 US disclosed
US-9035287-B2 Polymeric materials for use in metal-oxide-semiconductor field-effect transistors POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-9035287-B2 Polymeric materials for use in metal-oxide-semiconductor field-effect transistors POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-20140217395-A1 Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors POLYERA CORPORATION (US) 2014-08-07 US disclosed
US-20140217395-A1 Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors POLYERA CORPORATION (US) 2014-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240052103-A1 POLYMER AND TRIAZINE COMPOUND TERT, TERB1, MCM5 ALDH1A1 1603/4885KMT2A 735/4885TSHR 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.