Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.56 |
| ▸ | ESR1 | P03372 | 5/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16542335 | 0.87 | ACHE (0.58) | ESR2ESR1ACHETP53GAA | |
| SCHEMBL9623648 | 0.84 | MAOB (0.67) | ESR2ESR1MAOBGUSBPTPN1 | |
| SCHEMBL14455084 | 0.82 | ESR2 (0.63) | ESR2ESR1ACHETP53TDP1 | |
| SCHEMBL18308821 | 0.80 | ESR2 (0.67) | ESR2ESR1MAOBGUSBACHE | |
| SCHEMBL6068072 | 0.79 | TP53 (0.54) | ESR2ESR1ACHETP53TDP1 | |
| SCHEMBL15929645 | 0.79 | ACHE (0.44) | ESR2ESR1ACHETP53GAA | |
| SCHEMBL9938324 | 0.78 | ACHE (0.68) | ACHEMAPTSMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL14850872 | 0.78 | AKR1C3 (0.55) | ACHEPTPN1TP53GAAMAPT | |
| SCHEMBL11950304 | 0.77 | ACHE (0.56) | ESR2ESR1MAOBACHETP53 | |
| SCHEMBL18308823 | 0.76 | ESR2 (0.57) | ESR2ESR1MAOBGUSBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9035287-B2 | Polymeric materials for use in metal-oxide-semiconductor field-effect transistors | POLYERA CORPORATION (US) | 2015-05-19 | — | — | US | disclosed |
| US-20140217395-A1 | Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors | POLYERA CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |