Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16542335 | 0.87 | ACHE (0.58) | ACHECYP3A4ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL15932982 | 0.84 | CYP3A4 (0.41) | ACHECYP3A4ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL15929634 | 0.79 | ESR2 (0.56) | ACHECYP3A4ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL9938324 | 0.78 | ACHE (0.68) | ACHECYP3A4ALDH1A1MAPTL3MBTL4 | |
| SCHEMBL14850872 | 0.78 | AKR1C3 (0.55) | ACHECYP3A4ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL4977240 | 0.74 | ACHE (0.39) | ACHECYP3A4ALDH1A1MAPT | |
| SCHEMBL13069497 | 0.74 | ACHE (0.52) | ACHECYP3A4ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL13049508 | 0.74 | ACHE (0.47) | ACHECYP3A4ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL29038580 | 0.73 | MAPT (0.48) | ACHEALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL31547677 | 0.73 | TDP1 (0.52) | ACHECYP3A4ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9035287-B2 | Polymeric materials for use in metal-oxide-semiconductor field-effect transistors | POLYERA CORPORATION (US) | 2015-05-19 | — | — | US | disclosed |
| US-20140217395-A1 | Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors | POLYERA CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |