SCHEMBL15929638

SCHEMBL15929638

COc1cc(-c2ccc(O)cc2)c(C)cc1-c1ccc(C)cc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGAM O43451 10/20 0.53
GAA P10253 10/20 0.53
SI P14410 10/20 0.53
MGAM2 Q2M2H8 10/20 0.53
ESR2 Q92731 3/20 0.45
ESR1 P03372 1/20 0.45
ACHE P22303 1/20 0.43
GUSB P08236 1/20 0.43
ABL1 P00519 2/20 0.42
ABCB1 P08183 2/20 0.42
BCR P11274 2/20 0.42
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
CHEK2 O96017 1/20 0.40
FYN P06241 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15932980 0.86 MGAM (0.67) MGAMGAASIMGAM2ESR2
SCHEMBL15929640 0.86 ACHE (0.59) GAAESR2ESR1ACHEABL1
SCHEMBL10190449 0.84 MGAM (0.53) MGAMGAASIMGAM2ESR2
SCHEMBL14363397 0.81 MGAM (0.53) MGAMGAASIMGAM2ESR2
SCHEMBL18308821 0.81 ESR2 (0.67) MGAMGAASIMGAM2ESR2
SCHEMBL18308823 0.81 ESR2 (0.57) MGAMGAASIMGAM2ESR2
SCHEMBL14511833 0.80 MGAM (0.49) MGAMGAASIMGAM2ESR2
SCHEMBL10190451 0.80 ESR2 (0.56) GAAESR2ESR1ACHEABL1
SCHEMBL25742899 0.77 PGR (0.49) GAAESR2ALDH1A1KDM4E
SCHEMBL14513145 0.76 MGAM (0.56) MGAMGAASIMGAM2ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9035287-B2 Polymeric materials for use in metal-oxide-semiconductor field-effect transistors POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-20140217395-A1 Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors POLYERA CORPORATION (US) 2014-08-07 US disclosed