Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678598 | 0.86 | KDM4E (0.59) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL12028758 | 0.86 | KDM4E (0.59) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL2449268 | 0.85 | KDM4E (0.70) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL2449266 | 0.85 | KDM4E (0.70) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL2830674 | 0.83 | KDM4E (0.67) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL10572851 | 0.82 | KDM4E (0.59) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL10572842 | 0.82 | KDM4E (0.59) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL15929662 | 0.79 | RELA (0.57) | CYP3A4RELACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL9282701 | 0.78 | KDM4E (0.55) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL19523638 | 0.78 | KDM4E (0.50) | KDM4ECYP3A4LMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9035287-B2 | Polymeric materials for use in metal-oxide-semiconductor field-effect transistors | POLYERA CORPORATION (US) | 2015-05-19 | — | — | US | disclosed |
| US-20140217395-A1 | Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors | POLYERA CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |