Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | BCR | P11274 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572842 | 0.92 | KDM4E (0.59) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL10572851 | 0.92 | KDM4E (0.59) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL2830674 | 0.89 | KDM4E (0.67) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL2449268 | 0.87 | KDM4E (0.70) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL2449266 | 0.87 | KDM4E (0.70) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL5016574 | 0.82 | TRPA1 (0.80) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL29190687 | 0.82 | KDM4E (0.57) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL5016576 | 0.82 | TRPA1 (0.80) | KDM4ECYP3A4LMNATP53TSHR | |
| Para-Methoxy Cinnamaldehyde SCHEMBL1226375 | 0.81 | ALDH1A1 (0.53) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL566691 | 0.80 | ALDH1A1 (0.57) | KDM4ECYP3A4LMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5426136-A | Contacting so that equilibrium is approaehed at or slightly above or below criticla micelle concen | PPG INDUSTRIES, INC. (US) | 1995-06-20 | — | — | US | claimed |
| WO-1994021725-A1 | PARTICULATE AMORPHOUS SILICA ASSOCIATED WITH THIN POLYMERIC FILM | PPG INDUSTRIES, INC. (US) | 1994-09-29 | — | — | WO | claimed |
| US-5426136-A | Contacting so that equilibrium is approaehed at or slightly above or below criticla micelle concen | PPG INDUSTRIES, INC. (US) | 1995-06-20 | — | — | US | disclosed |
| WO-1994021725-A1 | PARTICULATE AMORPHOUS SILICA ASSOCIATED WITH THIN POLYMERIC FILM | PPG INDUSTRIES, INC. (US) | 1994-09-29 | — | — | WO | disclosed |