Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15929691 | 0.90 | MAPT (0.56) | ABCG2NPC1MAPTRAB9AMEN1 | |
| SCHEMBL15929679 | 0.85 | HTT (0.50) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL19318193 | 0.81 | HTT (0.57) | HTTSMN1; SMN2CYP1A2L3MBTL1 | |
| SCHEMBL15929670 | 0.81 | TRIM24 (0.40) | ABCG2NPC1MAPTRAB9AMEN1 | |
| SCHEMBL9982860 | 0.81 | ABCG2 (0.86) | ABCG2NPC1MAPTRAB9AMEN1 | |
| SCHEMBL9982858 | 0.81 | ABCG2 (0.86) | ABCG2NPC1MAPTRAB9AMEN1 | |
| SCHEMBL15807393 | 0.81 | NFE2L2 (0.68) | ABCG2NPC1MAPTRAB9AMEN1 | |
| SCHEMBL15929673 | 0.81 | HTT (0.47) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL15929602 | 0.75 | HTT (0.63) | HTTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL15929688 | 0.74 | HTT (0.58) | MAPTMEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9035287-B2 | Polymeric materials for use in metal-oxide-semiconductor field-effect transistors | POLYERA CORPORATION (US) | 2015-05-19 | — | — | US | disclosed |
| US-20140217395-A1 | Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors | POLYERA CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |