Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ADH1A | P07327 | 9/20 | 0.36 |
| ▸ | ADH1C | P00326 | 7/20 | 0.34 |
| ▸ | ADH4 | P08319 | 3/20 | 0.33 |
| ▸ | ADH1B | P00325 | 3/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19346834 | 1.00 | TSHR (0.50) | TSHRADH1AADH1CADH4ADH1B | |
| SCHEMBL24512544 | 1.00 | TSHR (0.50) | TSHRADH1AADH1CADH4ADH1B | |
| SCHEMBL14639970 | 0.97 | TSHR (0.53) | TSHRADH1AADH1CADH4ADH1B | |
| SCHEMBL14045426 | 0.97 | TSHR (0.53) | TSHRADH1AADH1CADH4ADH1B | |
| SCHEMBL13639014 | 0.93 | TSHR (0.48) | TSHRADH1AADH1CADH4ADH1B | |
| SCHEMBL6059416 | 0.90 | TSHR (0.43) | TSHR | |
| SCHEMBL7354255 | 0.90 | TSHR (0.50) | TSHR | |
| SCHEMBL13109225 | 0.89 | TSHR (0.43) | TSHRADH1AADH1CADH4ADH1B | |
| SCHEMBL20573718 | 0.87 | ADH1A (0.43) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL493755 | 0.84 | ADH1A (0.41) | ADH1AADH1CADH4ADH1BADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688607-B2 | No- and H2S-releasing compounds | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2017-06-27 | — | — | US | disclosed |
| US-20140221316-A1 | NO- AND H2S- RELEASING COMPOUNDS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221316-A1 | NO- AND H2S- RELEASING COMPOUNDS | PTGS1, NOS2, NOS1 | TSHR 2979/4885ADH1A 1922/4885ADH1C 3129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.