SCHEMBL15933508

SCHEMBL15933508

CCSc1cccnc1-c1nc2cc(SC(F)(F)F)ccc2o1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.36
▸ HPGD P15428 6/20 0.36
▸ KDM4E B2RXH2 6/20 0.36
▸ SMN1; SMN2 Q16637 5/20 0.36
▸ HSD17B10 Q99714 5/20 0.36
▸ RAB9A P51151 5/20 0.36
▸ NPC1 O15118 4/20 0.36
▸ TP53 P04637 4/20 0.36
▸ GAA P10253 2/20 0.35
▸ L3MBTL1 Q9Y468 3/20 0.34
▸ UTRN P46939 4/20 0.33
▸ POLB P06746 2/20 0.33
▸ PKM P14618 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ MAPT P10636 3/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29431601 1.00 ALDH1A1 (0.36) ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10
SCHEMBL17231821 0.87 CEPT1 (0.40) ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10
SCHEMBL20144325 0.85 ATR (0.33) SMN1; SMN2NPC1
SCHEMBL17309728 0.85 KDM4E (0.44) ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10
SCHEMBL19942795 0.84 TP53 (0.34) ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10
SCHEMBL15616835 0.84 NPC1 (0.43) ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10
SCHEMBL15846613 0.83 UTRN (0.38) ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10
SCHEMBL29431610 0.83 UTRN (0.38) ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10
SCHEMBL17309741 0.83 ALDH1A1 (0.37) ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10
SCHEMBL16612237 0.83 ALDH1A1 (0.41) ALDH1A1HPGDKDM4ESMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112021322-B Compositions and methods for controlling pests 住友化学株式会社 2022-04-01 — — CN disclosed
CN-112021322-A Compositions and methods for controlling pests 住友化学株式会社 2020-12-04 — — CN disclosed
EP-2952099-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-17 — — EP disclosed
EP-2952100-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-10 — — EP disclosed
EP-2952097-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-10 — — EP disclosed
US-9974307-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 — — US disclosed
US-9974307-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 — — US disclosed
EP-2938601-B1 FUSED OXAZOLE COMPOUNDS AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL CO (JP) 2018-05-16 — — EP disclosed
EP-2938601-B1 FUSED OXAZOLE COMPOUNDS AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL CO (JP) 2018-05-16 — — EP disclosed
US-9883675-B2 Method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-06 — — US disclosed
US-20150359223-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
US-20150359223-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
US-20150359219-A1 PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
EP-2952100-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
EP-2952097-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
EP-2952098-A1 PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
EP-2952099-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
US-20150313234-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-05 — — US disclosed
US-20150313234-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-05 — — US disclosed
WO-2014119699-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD 住友化学株式会社 (JP) 2014-08-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150313234-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL AFF1, AFF2, PYM1 ALDH1A1 1355/4885HPGD 3739/4885KDM4E 2940/4885
US-20150359223-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS PNPO, NAMPT, NNT ALDH1A1 3135/4885HPGD 803/4885KDM4E 187/4885
US-20150359219-A1 PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PEST ABAT, PNPO, GABBR1 ALDH1A1 2944/4885HPGD 4470/4885KDM4E 380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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